• Question: What type of diabetes? Or is it all of then and what type of eye disease and cancer?

    Asked by Sanah? to Jenny on 4 Nov 2016.
    • Photo: Jenny Batson

      Jenny Batson answered on 4 Nov 2016:


      Hi Sanah
      We’re looking at diabetic nephropathy (kidney disease), neuropathy (nerve disorders) and diabetic retinopathy (eye disease) because our lab discovered a variant of a protein called VEGF, which is protective against damage caused by glucose toxicity and normalises blood vessels back to a more healthy state. All of these can be caused by type I or type II diabetes. Did you know that 20-30% of patients with type I or type II diabetes develop nephropathy, and as diabetes increases these diseases will increase too.
      For eye disease we’re starting with age-related macular degeneration and diabetic macular oedema but it can be any eye disease that is causes by abnormal blood vessel growth.
      We know our approach works in the lab in prostate, colon and breast cancers but may work in a lot more so part of the work we’re doing now is working out which cancer type and which patients will have most benefit from our drugs.
      Jenny

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